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Roszet contains two medicines, rosuvastatin and ezetimibe, to lower cholesterol. Roszet is usedf along with diet in adults with high blood cholesterol levels to reduce low density lipoprotein cholesterol (LDL-C) or bad cholesterol. Also it is used alone or together with other LDL-lowering medicines in adults with a type of high cholesterol called homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C.